Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0285	CCND1	tumor	N/A	N/A	N/A	regulation	Binding to TLS protein induces TLS allosteric change, allowing interaction with cyclin D1, inhibiting CBP and p300 activity, and silencing cyclin D1 gene expression.	22996375	LncRNADisease
EL0289	CDKN2B-AS1	tumor	N/A	N/A	N/A	N/A	Long ncRNA antisense non-coding RNA in the INK4 locus (ANRIL) has been associated to hereditary cutaneous malignant melanoma, prostate cancer and tumors of the neural system (Pasmant et al., 2011).	24624135	LncRNADisease
EL0289	CDKN2B-AS1	tumor	N/A	N/A	N/A	regulation	ANRIL, GAS5 and lincRNA-p23 are involved in the escape of growth suppression by regulating tumor suppressor genes (ANRIL) or apoptosis regulators.	24667321	LncRNADisease
EL0526	GAS5	tumor	N/A	N/A	N/A	regulation	Binding to GR as a decoy and blocking transcriptional induction by GR, induces growth arrest and apoptosis.	22996375	LncRNADisease
EL0526	GAS5	tumor	N/A	N/A	N/A	regulation	ANRIL, GAS5 and lincRNA-p23 are involved in the escape of growth suppression by regulating tumor suppressor genes (ANRIL) or apoptosis regulators.	24667321	LncRNADisease
EL0526	GAS5	tumor	N/A	N/A	N/A	regulation	Our own work suggests that while RoR (Zhang et al., 2013a) may function as an oncogene through suppression of p53 in response to DNA damage, loc285194 (Liu et al., 2013) and GAS5 (Zhang et al., 2013b) may play a tumor suppressive role through the “competitive endogenous RNA” (CeRNA) mechanism (Salmena et al., 2011).	24721780	LncRNADisease
EL0556	H19	tumor	N/A	N/A	N/A	epigenetics	In recent years, we have extensively investigated the expression of the H19 gene in a number of human cancers and explored the role of H19 RNA in tumor development.	23429271	LncRNADisease
EL0556	H19	tumor	N/A	N/A	N/A	expression	H19, a lncRNA with oncogenic properties, is upregulated in a wide range of tumours.	23660942	LncRNADisease
EL0556	H19	tumor	N/A	N/A	N/A	regulation	Oncofetal H19 RNA promotes tumor metastasis.	24703882	LncRNADisease
EL0853	MALAT1	tumor	N/A	N/A	N/A	regulation	MALAT1 plays a role in cell migration and tumor metastasis, as demonstrated by knockout of MALAT1 in lung cancer cell lines (Gutschner et al., 2013).	24721780	LncRNADisease
EL1097	PTENP1	tumor	N/A	N/A	N/A	regulation	An example of this mechanism is represented by the tumour suppressor gene PTEN and its pseudogene PTENP1.	23660942	LncRNADisease
EL1098	PTENP1-AS	tumor	N/A	N/A	N/A	regulation	We characterize a previously unidentified PTENpg1-encoded antisense RNA (asRNA), which regulates PTEN transcription and PTEN mRNA stability. We find two PTENpg1 asRNA isoforms, α and β. The α isoform functions in trans, localizes to the PTEN promoter and epigenetically modulates PTEN transcription by the recruitment of DNA methyltransferase 3a and Enhancer of Zeste. In contrast, the β isoform interacts with PTENpg1 through an RNA-RNA pairing interaction, which affects PTEN protein output through changes of PTENpg1 stability and microRNA sponge activity.	23435381	LncRNADisease
EL1365	Trp53cor1	tumor	N/A	N/A	N/A	regulation	Global gene repression in the p53 transcriptional response by binding hnRNP-K, inducing cellular apoptosis.	22996375	LncRNADisease
EL1365	Trp53cor1	tumor	N/A	N/A	N/A	regulation	Thus, similar to its activator p53, lincRNA-p21 may play an important role in tumour suppression by operating as a transcriptional repressor.	23660942	LncRNADisease
EL1365	Trp53cor1	tumor	N/A	N/A	N/A	regulation	Global gene regulation p53 repression via hnRNP-K; inducing cellular apoptosis	24499465	LncRNADisease
EL1365	Trp53cor1	tumor	N/A	N/A	N/A	regulation	ANRIL, GAS5 and lincRNA-p23 are involved in the escape of growth suppression by regulating tumor suppressor genes (ANRIL) or apoptosis regulators.	24667321	LncRNADisease