INTERACTION |
ID |
lncRNA Name |
Interaction target |
Level of interaction |
Type of interaction |
Description |
PMID |
Source |
EL0575 |
HNF1A-AS1 |
cyclin D1, E-cadherin, N-cadherin and β-catenin |
RNA-Protein |
regulation |
HNF1A-AS1 was determined to promote tumor proliferation and metastasis, both in vitro and in vivo, by regulating cyclin D1, E-cadherin, N-cadherin and β-catenin expression. In addition, the binding of HNF1A-AS1 to DNMT1 may explain its regulation of E-cadherin. |
25863539 |
|
EL0575 |
HNF1A-AS1 |
CEA, CA19-9, RRM1 |
RNA-Protein |
regulation |
Low HNF1A-AS1 expression was associated with tumor size/diameter (p = 0.005, multivariate analysis), levels of serum carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9), and RRM1 expression in tissue samples (p = 0.028, p = 0.009, and p = 0.006, respectively). |
26472090 |
|
EL0575 |
HNF1A-AS1 |
Bcl-2 |
RNA-Protein |
regulation |
HNF1A-AS1 functioned as an oncogene in tumor growth and apoptosis through sponging tumor-suppressive hsa-miR-30b-5p (miR-30b) and de-repressing Bcl-2. |
27084450 |
|
EL0575 |
HNF1A-AS1 |
miR-30b |
RNA-RNA |
binding |
HNF1A-AS1 functioned as an oncogene in tumor growth and apoptosis through sponging tumor-suppressive hsa-miR-30b-5p (miR-30b) and de-repressing Bcl-2. |
27084450 |
|
|