| INTERACTION | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||
| EL0575 | HNF1A-AS1 | cyclin D1, E-cadherin, N-cadherin and β-catenin | RNA-Protein | regulation | HNF1A-AS1 was determined to promote tumor proliferation and metastasis, both in vitro and in vivo, by regulating cyclin D1, E-cadherin, N-cadherin and β-catenin expression. In addition, the binding of HNF1A-AS1 to DNMT1 may explain its regulation of E-cadherin. | 25863539 | |||
| EL0575 | HNF1A-AS1 | CEA, CA19-9, RRM1 | RNA-Protein | regulation | Low HNF1A-AS1 expression was associated with tumor size/diameter (p = 0.005, multivariate analysis), levels of serum carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9), and RRM1 expression in tissue samples (p = 0.028, p = 0.009, and p = 0.006, respectively). | 26472090 | |||
| EL0575 | HNF1A-AS1 | Bcl-2 | RNA-Protein | regulation | HNF1A-AS1 functioned as an oncogene in tumor growth and apoptosis through sponging tumor-suppressive hsa-miR-30b-5p (miR-30b) and de-repressing Bcl-2. | 27084450 | |||
| EL0575 | HNF1A-AS1 | miR-30b | RNA-RNA | binding | HNF1A-AS1 functioned as an oncogene in tumor growth and apoptosis through sponging tumor-suppressive hsa-miR-30b-5p (miR-30b) and de-repressing Bcl-2. | 27084450 | |||