INTERACTION
ID lncRNA Name Interaction target Level of interaction Type of interaction Description PMID Source
EL0514 FTX Xist RNA-RNA regulation The Ftx mutation, however, results in widespread alteration of transcript levels within the X-inactivation center (Xic) and particularly important decreases in Xist RNA levels. 21118898
EL0514 FTX RIG-I RNA-Protein regulation Ectopic expression of RIG-I abrogated the effects of lncRNA Ftx or miR-545 on HCC cells. LncRNA Ftx/miR-545-mediated downregulation of RIG-I led to increased Akt phosphorylation in vitro and in vivo. 26992218
EL0514 FTX miR-545 , RIG-I RNA-RNA co-expression MiR-545 was positively correlated with lncRNA Ftx expression. 26992218
EL0514 FTX PI3K/Akt signaling N/A regulation The novel pathway lncRNA Ftx/miR-545/RIG-I promotes HCC development by activating PI3K/Akt signaling. 26992218
EL0515 Ftx XIST RNA-DNA regulation Ftx has both a global role in the adjustment of the transcription levels of several genes in the Xic and a positive effect on Xist expression that coincides with a role in preventing the methylation of the Xist promoter. 21329697 LncRNADisease
EL0515 Ftx XIST RNA-RNA co-expression Ftx is upregulated specifically in female cells at the time of Xist upregulation and X inactivation. 21496640 LncRNADisease