INTERACTION |
ID |
lncRNA Name |
Interaction target |
Level of interaction |
Type of interaction |
Description |
PMID |
Source |
EL0514 |
FTX |
Xist |
RNA-RNA |
regulation |
The Ftx mutation, however, results in widespread alteration of transcript levels within the X-inactivation center (Xic) and particularly important decreases in Xist RNA levels. |
21118898 |
|
EL0514 |
FTX |
RIG-I |
RNA-Protein |
regulation |
Ectopic expression of RIG-I abrogated the effects of lncRNA Ftx or miR-545 on HCC cells. LncRNA Ftx/miR-545-mediated downregulation of RIG-I led to increased Akt phosphorylation in vitro and in vivo. |
26992218 |
|
EL0514 |
FTX |
miR-545 , RIG-I |
RNA-RNA |
co-expression |
MiR-545 was positively correlated with lncRNA Ftx expression. |
26992218 |
|
EL0514 |
FTX |
PI3K/Akt signaling |
N/A |
regulation |
The novel pathway lncRNA Ftx/miR-545/RIG-I promotes HCC development by activating PI3K/Akt signaling. |
26992218 |
|
EL0515 |
Ftx |
XIST |
RNA-DNA |
regulation |
Ftx has both a global role in the adjustment of the transcription levels of several genes in the Xic and a positive effect on Xist expression that coincides with a role in preventing the methylation of the Xist promoter. |
21329697 |
LncRNADisease
|
EL0515 |
Ftx |
XIST |
RNA-RNA |
co-expression |
Ftx is upregulated specifically in female cells at the time of Xist upregulation and X inactivation. |
21496640 |
LncRNADisease
|
|