Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0289 CDKN2B-AS1 serous ovarian cancer qPCR, Western blot, knockdown etc. SOC tissue, cell lines (SK-OV-3, HO8910) up-regulated interaction We found that ANRIL levels were elevated in SOC tissues compared with normal controls and were highly correlated with advanced FIGO stage, high histological grade, lymph node metastasis, and poor prognosis. Functional studies suggest a critical role of ANRIL in the control of SOC cell migration/invasion at least in part through regulation of MET and MMP3. 25845387 Lnc2Cancer
EL0578 HOTAIR serous ovarian cancer qPCR, knockdown etc. cell lines (A2780, Hey, SKOV3, OVCA429, OVCA433, OVCAR3) up-regulated expression We found that HOTAIR levels were overexpressed in SOC tissues compared with normal controls and that HOTAIR overexpression was correlated with an advanced FIGO stage and a high histological grade. HOTAIR knockdown resulted in the induction of cell cycle arrest and apoptosis through certain cell cycle-related and apoptosis-related proteins. 25796453 Lnc2Cancer