Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0227 BANCR hepatocellular carcinoma quantitative real-time PCR (qRT-PCR), overexpression, downregulation, flow cytometry, and transwell invasion and migration assays human hepatocellular carcinoma tissues up-regulated expression BANCR may contribute to HCC initiation and progression and would be used as not only a novel prognostic marker but also a potential therapeutic target for this disease. 26758762
EL0310 CTBP1-AS hepatocellular carcinoma RT-qPCR serum N/A N/A high sensitivity and specificity for discriminating HCC from healthy controls and also from CHC patients 27113935
EL0575 HNF1A-AS1 hepatocellular carcinoma N/A HCC tissue and cell line up-regulated N/A sponging tumor-suppressive hsa-miR-30b-5p (miR-30b) and de-repressing Bcl-2 27084450
EL0600 HULC hepatocellular carcinoma qPCR, Western blot, Luciferase reporter assay etc. HCC tissue, cell lines (L-O2 cell line, L-O2-X) up-regulated expression Our data show that an lncRNA, HULC, is responsible for the perturbations in circadian rhythm through upregulating circadian oscillator CLOCK in hepatoma cells, resulting in the promotion of hepatocarcinogenesis. Mechanistically, the complementary base pairing between HULC and the 5'untranslated region of CLOCK mRNA underlay the HULC-modulated expression of CLOCK, and the mutants in the complementary region failed to achieve the event. 25622901 Lnc2Cancer
EL0853 MALAT1 hepatocellular carcinoma N/A hepatocellular carcinoma (HCC) tissues up-regulated interaction N/A 26352013
EL0861 MEG3 hepatocellular carcinoma methylation specific PCR (MSP), qRT-PCR, RNA pulldown and western blot analysis, MTT assay, fluorescence microscopy and flow cytometry, improved MS2 biotin tagged RNA affinity purification method hepatoma HepG2 and Huh7 cells up-regulated interaction Ectopic expression of MEG3 inhibited hepatoma cell growth in a time-dependent manner, resulted in cell cycle arrest and induced apoptosis. Adenosine increases MEG3 expression by inhibition of DNA methylation and its antitumor effects is involved in MEG3 activation. 26647875
EL1363 TRERNA1 hepatocellular carcinoma N/A hepatoma cells N/A expression miR-190a can silence treRNA post-transcriptionally. Suppression of treRNA by miR-190a led to significant changes of mesenchymal-epithelial transition markers and impaired migration and invasion capability of hepatoma cells. 26608035