Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0289	CDKN2B-AS1	diabetes mellitus	N/A	N/A	N/A	expression	ANRIL is a recently discovered long non-coding RNA encoded in the chromosome 9p21 region. This locus is a hotspot for disease-associated polymorphisms, and it has been consistently associated with cardiovascular disease, and more recently with several cancers, diabetes, glaucoma, endometriosis among other conditions.	23104877	LncRNADisease
EL0289	CDKN2B-AS1	diabetes mellitus	N/A	N/A	N/A	mutation	Genetic variation in lncRNA genes causes disease and influences susceptibility	23791884	LncRNADisease
EL0853	MALAT1	diabetes mellitus	N/A	N/A	N/A	expression	In addition, MALAT1, a conserved lncRNA, was significantly upregulated in an RF/6A cell model of hyperglycemia, in the aqueous humor samples, and in fibrovascular membranes of diabetic patients.	24436191	LncRNADisease
EL0853	MALAT1	diabetes mellitus	N/A	N/A	N/A	N/A	MALAT1 expression is significantly upregulated in the retinas of STZ-induced diabetic rats and db/db mice. MALAT1 knockdown could obviously ameliorate DR in vivo, as shown by pericyte loss, capillary degeneration, microvascular leakage, and retinal inflammation. Moreover, MALAT1 knockdown could regulate retinal endothelial cell proliferation, migration, and tube formation in vitro. The crosstalk between MALAT1 and p38 MAPK signaling pathway is involved in the regulation of endothelial cell function.	25356875	LncRNADisease
EL0862	Meg3	diabetes mellitus	MEG3 knockdown	STZ-induced diabetic mice	N/A	N/A	knockdown also regulates retinal endothelial cell proliferation, migration, and tube formation in vitro	26845358
EL1034	P2rx3	diabetes mellitus	reverse transcription-polymerase chain reaction (RT-PCR), immunohistochemistry, and western blotting	diabetic rat dorsal root ganglia (DRG) Diabetes mellitus (DM) patients' serum samples	up-regulated	interaction	Uc.48+ siRNA treatment may alleviate the DNP by inhibiting the excitatory transmission mediated by the P2X3 receptor in DRG.	26686228