Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0028 AC100865.1 coronary artery disease microarray, qPCR plasma from coronary artery disease (CAD) patients up-regulated expression The present study screened lncRNAs by microarray analysis in the plasma from CAD patients and control individuals and found that 265 lncRNAs were differentially expressed. Receiver operating characteristic (ROC) curve analysis showed that lncRNA AC100865.1(referred to as CoroMarker) was the best of these lncRNAs. 26201019
EL0289 CDKN2B-AS1 coronary artery disease N/A N/A N/A mutation Sequence polymorphisms in a 58-kilobase (kb) interval on chromosome 9p21 confer a markedly increased risk (rs3217992, A>G;rs1063192, C>T) of coronary artery disease (CAD), the leading cause of death worldwide. 17554300 LncRNADisease
EL0289 CDKN2B-AS1 coronary artery disease N/A N/A N/A mutation Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs (rs2891168, A>G) in the ANRIL locus on chromosome 9p. 18048406 LncRNADisease
EL0289 CDKN2B-AS1 coronary artery disease N/A N/A N/A expression Significantly reduced expression of all INK4/ARF transcripts (p15(INK4b), p16(INK4a), ARF and ANRIL) was found in PBTL of individuals harboring a common SNP (rs10757278) associated with increased risk of coronary artery disease, stroke and aortic aneurysm. 19343170 LncRNADisease
EL0289 CDKN2B-AS1 coronary artery disease N/A N/A N/A expression Whole blood RNA expression of the short variants of ANRIL was increased by 2.2-fold whereas expression of the long ANRIL variant was decreased by 1.2-fold in healthy subjects homozygous for the risk allele. Expression levels of the long and short ANRIL variants were positively correlated with that of the cyclin-dependent kinase inhibitor, CDKN2B (p15) and TDGF1 (Cripto), respectively. 19592466 LncRNADisease
EL0289 CDKN2B-AS1 coronary artery disease N/A N/A N/A expression However, overexpression of 1 ANRIL variant altered the expression of many genes involved in nuclear regulation and chromatin architecture, indicating diverse trans-regulatory effects that go beyond the cis-effects seen at 9p21. 23104877 LncRNADisease
EL0556 H19 coronary artery disease N/A N/A N/A N/A Re-expression of H19 has been observed in patients with atherosclerosis. Common polymorphisms of H19 are associated with the risk and severity of CAD in a Chinese population. 25772106 LncRNADisease