| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation | Genotypes of rs10757278 linked to increased risk of atherosclerotic diseases are also associated with decreased expression in PBTL of the INK4/ARF locus, near CDKN2B-AS1 locus. | 19343170 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | expression | 9p21.3 may promote atherosclerosis by regulating expression of ANRIL, which in turn is associated with altered expression of genes controlling cellular proliferation pathways. | 19592466 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation/expression | Transcripts EU741058 and NR_003529 of antisense noncoding RNA in the INK4 locus (ANRIL) were significantly increased in carriers of the risk haplotype. | 20056914 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | Interaction | ANRIL abundantly expressed in atherosclerotic lesions. ANRIL DQ485454 which is not genetically determined by the 9p21 genotype was significantly correlated with MTAP expression. | 20637465 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | locus | A genetic susceptibility locus. | 20956613 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation | Individuals homozygous for the atherosclerotic risk allele (rs3217992, A>G;rs1063192, C>T) show decreased expression of ANRIL. | 21151960 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | expression | Gene expression studies have found that expression levels of CDKN2A/CDKN2B/ANRIL are co-regulated and associated with the risk haplotype and atherosclerosis severity. | 21550161 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation | The risk alleles for atherosclerosis-related phenotypes were consistently associated with a lower expression of ANRIL when evaluating exons 1-2. Common carotid artery stenosis was associated with a significantly lower (P<0.01) expression of ANRIL (exons 1-2). ANRIL knock-down in VSMC caused significant variation in expression of CDKN2A/B (P<0.05) and reduction of cell growth (P<0.05) in vitro. | 22178423 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation | Genetic variation in lncRNA genes causes disease and influences susceptibility | 23791884 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | regulation | The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10. | 23813974 | LncRNADisease |
| EL0289 | CDKN2B-AS1 | atherosclerosis | N/A | N/A | N/A | mutation | Chr9p21 encodes the long non-coding RNA (ncRNA) antisense non-coding RNA in the INK4 locus (ANRIL). ANRIL expression is associated with the Chr9p21 genotype and correlated with atherosclerosis severity | 23861667 | LncRNADisease |
| EL0556 | H19 | atherosclerosis | N/A | N/A | N/A | epigenetics | The most pronounced differences of atherosclerotic plaques in DNA methylation levels were registered for a site which is located in CpG-island of imprinted gene H19. | 21954592 | LncRNADisease |
| EL0600 | HULC | atherosclerosis | N/A | liver cancer | up-regulated | N/A | HULC regulated TNF-α-induced apoptosis through regulation of miR-9 expression | 26981838 | |
| EL1166 | RP5-833A20.1 | atherosclerosis | N/A | N/A | N/A | N/A | Using microarray analysis, the authors found that long noncoding RNA RP5-833A20.1 expression was upregulated, whereas nuclear factor IA (NFIA) expression was downregulated in human acute monocytic leukemia macrophage-derived foam cells. Moreover, they showed that long noncoding RNA RP5-833A20.1 maydecreases NFIA expression by inducing hsa-miR-382-5p expression in vitro. | 25265644 | LncRNADisease |
| EL1349 | TP53COR1 | atherosclerosis | N/A | N/A | N/A | N/A | The expression of lincRNA-p21 was dramatically downregulated in atherosclerotic plaques of ApoE(-/-) mice, an animal model for atherosclerosis. LincRNA-p21 represses cell proliferation and induces apoptosis in vascular smooth muscle cells and mouse mononuclear macrophage cells in vitro | 25156994 | LncRNADisease |