LncRNA Information
ID EL1138 Name Gm37494 Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class lncRNA NCBI accession N/A
Ensembl N/A Sequence N/A Peptide-related N/A
CircRNA N/A Exosomal yes Structure N/A


Disease
Disease Drug/chemo/stress Method Sample Expression pattern Dysfunction type Description PMID
spinal cord injury qRT-PCR, western blot, RNA-seq, Luciferase reporter assays, ELISA, Knockdown, Overexpression, immunofluorescence C57BL/6 mice, ADSC cells, BV2 microglial cell line up-regulated interaction HExos repair SCI by delivering lncGm37494, advising that lncGm3749 functions importantly in microenvironmental regulation and shows possibility for SCI treatments. 32307615


Interaction
Interaction target Level of interaction Type of interaction Methods Description PMID
miR-130b-3p RNA-RNA regulation western blot, ELISA LncGm37494 expression was significantly higher in HExos than Exos, and its upregulation promoted microglial M1/M2 polarization by inhibiting miR-130b-3p and promoting PP ARγ expression, as shown by luciferase reporter experiments. 32307615
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