| LncRNA Information | |||||
|---|---|---|---|---|---|
| ID | EL0334 | Name | ASP | Aliases | N/A |
| Species | Human Immunodeficiency Virus | Chromosome | N/A | Start site | N/A |
| End site | N/A | Chain | N/A | Exon NO. | N/A |
| Assembly | N/A | Class | lncRNA | NCBI accession | N/A |
| Ensembl | N/A | Sequence | N/A | Peptide-related | N/A |
| CircRNA | N/A | Exosomal | N/A | Structure | N/A |
| Function (not disease relevant) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug/chemo/stress | Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | ||
| Jurkat cells | interaction | The HIV-1 ASP transcript promotes epigenetic silencing of the HIV-1 5'LTR and proviral latency through the PRC2 pathway. | 28340355 | |||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Methods | Description | PMID | ||||
| PRC2 | RNA-Protein | binding | N/A | This transcript interacts with and recruits PRC2 to the HIV-1 5'LTR, increasing accumulation of the suppressive epigenetic mark H3K27me3, while reducing RNA Polymerase II and thus proviral transcription. | 28340355 | ||||
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