LncRNA Information
ID EL1439 Name URHC Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
hepatocelluar carcinoma microarray, qPCR, Western blot etc. hepatocellular cancer tissue, cell lines (DMEM, Gibco, Gaithersburg, MD, USA etc.) up-regulated N/A We confirmed that URHC expression was up-regulated in 30 HCC cases (57.7%) and that its higher expression was correlated with poor overall survival. We further demonstrated that URHC inhibition reduced cell proliferation and promoted apoptosis. high URHC expression can promote cell proliferation and inhibit apoptosis by repressing ZAK expression through inactivation of the ERK/MAPK pathway. 25013376 Lnc2Cancer