LncRNA Information
ID EL1350 Name TP53TG1 Aliases LINC00096; NCRNA00096; P53TG1; P53TG1-D; TP53AP1
Species Homo sapiens Chromosome 7 Start site 87325225
End site 87345515 Chain minus Exon NO. 3
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_015381
Ensembl ENSG00000182165 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
non-small cell lung cancer microarray, qPCR, Western bolt, knockdown etc. cell lines (A549, CDDP etc.) down-regulated N/A For lncRNA, the results showed that AK123263, CES1P1-001, RP3-508I15.14, AK126698, TP53TG1, and AC090952.4.1 decreased, whereas uc003bgl.1 and NCRNA00210 increased in A549/CDDP (all P <0.05). Cisplatin resistance in non-small-cell lung cancer cells may relate to the changes in noncoding RNAs. Among these, AK126698 appears to confer cisplatin resistance by targeting the Wnt pathway. 23741487 Lnc2Cancer
ataxia telangiectasia N/A human T lymphocytes from patient with ataxia telangiectasia (AT) up-regulated expression TP53TG1 demonstrated a weak up-regulation, reaching a maximum of 1.5-fold at 24 h after radiation exposure 25738893
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
TP53 DNA-TF regulation TP53 target gene 1 9713990 LncRNADisease