| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1168 | Name | RPL34-AS1 | Aliases | RP11-462C24.1; FLJ37673; RPL34-AS1 | |
| Species | Homo sapiens | Chromosome | 4 | Start site | 108538190 | |
| End site | 108620460 | Chain | minus | Exon NO. | 4 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_026968 | |
| Ensembl | ENSG00000234492 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| colorectal cancer | microarray, qPCR etc. | CRC tissue | down-regulated | N/A | We found that RP11-462C24.1 expression level was lower in cancer tissues compared with adjacent normal samples. Furthermore, its expression level was lower in CRC patients with metastasis than those without metastasis. That is, RP11-462C24.1 expression level decreased as the malignant degree of CRC increased. In addition, low expression of RP11-462C24.1 significantly correlated with more distant metastasis. | 24908062 | Lnc2Cancer | ||
| gastric cancer | microarray, qPCR etc. | gastric cancer tissue, cell lines (HCG-27, SGC-7901) | down-regulated | expression | Linc00261, DKFZP434K028 and RPL34-AS1 had lower expression levels in gastric cancer tissues than the normal counterparts. In gastric cell lines, the three lncRNAs were also down-regulated compared with the respective normal gastric epithelial cell line GES-1. Moreover, the low expression levels of DKFZP434K028 and RPL34-AS1 positively correlated with the larger tumor size. | 26237576 | Lnc2Cancer | ||