hepatocelluar carcinoma |
microarray, qPCR etc. |
cell lines (Hep3B, HepG2, SMMC-7721, MHCC-97L, MHCC-97H, HCCLM3 etc.) |
up-regulated |
expression |
The most upregulated lncRNAs in H2 were RP11-672F9.1, RP5-1014O16.1, and RP11-501G6.1, while the most downregulated ones were lincRNA-TSPAN8, lincRNA-CALCA, C14orf132, NCRNA00173, and CR613944. RP5- 1014O16.1 was highly expressed in high lymphatic metastatic potential HCC cell lines, while lowly expressed in no lymphatic metastatic potential HCC cell lines.We demonstrated that a large number of lncRNAs may play important roles in driving HCC cells to metastasize to different sites; these lncRNAs may provide novel molecular biomarkers and offer a new basis for combating metastasis in HCC cases. |
25556502 |
Lnc2Cancer
|