| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1107 | Name | RAD51-AS1 | Aliases | TODRA | |
| Species | Homo sapiens | Chromosome | 15 | Start site | 40686724 | |
| End site | 40695107 | Chain | minus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | retained intron | NCBI accession | NR_040058 | |
| Ensembl | ENSG00000245849 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| breast cancer | over-expression | Hela cells | up-regulated | locus | Our results identify TPIP as a novel E2F1 co-activator, suggest a similar role for other TPTEs, and indicate that the TODRA lncRNA affects RAD51 dysregulation and RAD51-dependent DSB repair in malignancy . Our results identify TPIP as a novel E2F1 co-activator, suggest a similar role for other TPTEs, and indicate that the TODRA lncRNA affects RAD51 dysregulation and RAD51-dependent DSB repair in malignancy. | 26230935 | |||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| RAD51 | RNA-Protein | regulation | Our results identify TPIP as a novel E2F1 co-activator, suggest a similar role for other TPTEs, and indicate that the TODRA lncRNA affects RAD51 dysregulation and RAD51-dependent DSB repair in malignancy. | 26230935 | |||||