| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL1067 | Name | PICSAR | Aliases | C21orf113; LINC00162; NCRNA00162; NLC1-C; NLC1C; PRED74 | |
| Species | Homo sapiens | Chromosome | 21 | Start site | 44999208 | |
| End site | 45004727 | Chain | minus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_024089 | |
| Ensembl | ENSG00000275874 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| testicular embryonal carcinoma | microarray, qPCR, knockdown, Western blot, Northern blot, RIP, RNA pull-down assay etc. | testicular tissue, cell lines(NTERA-2, NCCIT, HEK293 T cell) | down-regulated | interaction | NLC1-C, also known as long intergenic non-protein-coding RNA162 (LINC00162), was down-regulated in the cytoplasm and accumulated in the nucleus of spermatogonia and primary spermatocytes in the testes of infertile men with mixed patterns of MA compared with normal control. The accumulation of NLC1-C in the nucleus repressed miR-320a and miR-383 transcript and promoted testicular embryonal carcinoma cell proliferation by binding to Nucleolin. | 26539909 | Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| miR-320a and miR-383 | RNA-DNA | regulation | NLC1-C in the nucleus repressed miR-320a and miR-383 transcript and promoted testicular embryonal carcinoma cell proliferation by binding to Nucleolin. | 26539909 | |||||