| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0882 | Name | MIR7-3HG | Aliases | C19orf30; Huh7; LINC00306; NCRNA00306; PGSF1; uc002mbe.2 | |
| Species | Homo sapiens | Chromosome | 19 | Start site | 4769140 | |
| End site | 4772533 | Chain | plus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_027148 | |
| Ensembl | ENSG00000176840 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| liver cancer | microarray, qPCR etc. | liver cancer tissue, cell lines (Huh7, Bel7402, Bel7721, HepG2 etc.) | down-regulated | N/A | Compared with normal human hepatocytes and adjacent noncancerous tissues, uc002mbe.2 expression level was significantly lower in the HCC cell lines and liver cancer tissues. The TSA-induced uc002mbe.2 expression was positively correlated with the apoptotic effect of TSA in HCC cells. Therefore, TSA-induced apoptosis of HCC cells is uc002mbe.2 dependent and reduced expression of uc002mbe.2 may be associated with liver carcinogenesis. | 23643933 | Lnc2Cancer | ||
| hepatocelluar carcinoma | N/A | N/A | N/A | expression | Besides, another study showed that liver cancer-downregulated lncRNA uc002mbe.2 could be induced by trichostatin A (TSA) treatment and its expression is positively correlated with the apoptotic effect of TSA in HCC cells. | 24296588 | LncRNADisease | ||