| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0859 | Name | MDC1-AS1 | Aliases | MDC1-AS | |
| Species | Homo sapiens | Chromosome | 6 | Start site | 30703067 | |
| End site | 30713184 | Chain | plus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | antisense | NCBI accession | NR_133647 | |
| Ensembl | ENSG00000224328 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| bladder cancer | microarray, qPCR etc. | bladder cancer tissue | down-regulated | interaction | The expression levels of MDC1-AS and MDC1 was down-regulated in bladder cancer. After over-expression of MDC1-AS, increased levels of MDC1 were observed in bladder cancer cells. We also found a remarkably inhibitory role of antisense lncRNA MDC1-AS on malignant cell behaviors in bladder cancer cells EJ and T24. | 25514464 | Lnc2Cancer | ||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| MDC1 | RNA-DNA | regulation | we have identified a novel antisense lncRNA MDC1-AS, which may participate in bladder cancer through up-regulation of its antisense tumor-suppressing gene MDC1. | 25514464 | |||||