LncRNA Information
ID	EL0831	Name	LOC401317	Aliases	N/A
Species	Homo sapiens	Chromosome	7	Start site	N/A
End site	N/A	Chain	N/A	Exon NO.	N/A
Assembly	N/A	Class	N/A	NCBI accession	N/A
Ensembl	N/A	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
nasopharyngeal carcinoma	microarray, qPCR, Western blot, knockdown, Luciferase reporter assay etc.	cell lines (HNE2, HNE1, CNE2)	up-regulated	regulation	LOC401317 was the most significantly upregulated lncRNA. Further studies indicated that LOC401317 is diretcly regulated by p53 and that etcopic expression of LOC401317 inhibits HNE2 cell proliferation in vitro and in vivo by inducing cell cycle arrest and apoptosis. LOC401317 inhibited cell cycle progression by increasing p21 expression and decreasing cyclin D1 and cyclin E1 expression and promoted apoptosis through the induction of poly(ADP-ribose) polymerase and caspase-3 cleavage.	25422887	Lnc2Cancer

Interaction
Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
TP53	RNA-DNA	regulation	Further studies indicated that LOC401317 is directly regulated by p53 and that ectopic expression of LOC401317 inhibits HNE2 cell proliferation in vitro and in vivo by inducing cell cycle arrest and apoptosis.	25422887