| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0694 | Name | LINC01419 | Aliases | LVCAT7; TCONS_00014497 | |
| Species | Homo sapiens | Chromosome | 8 | Start site | 83403758 | |
| End site | 83408900 | Chain | plus | Exon NO. | 2 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_122034 | |
| Ensembl | ENSG00000253898 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| hepatocelluar carcinoma | microarray, qPCR etc. | HBV-related HCC tissue | up-regulated | expression | Four upregulated lncRNAs were randomly selected and analyzed for their expression levels in tissue samples from 14 HBV-related HCC patients. The corresponding non-tumor tissues were analyzed via qPCR, in which the obtained results are consistent with the microarray data. | 26109807 | Lnc2Cancer | ||
| hepatocelluar carcinoma | microarray, qPCR etc. | HCC tissue | up-regulated | expression | We noted that LINC01419 was characterized by a significant increase in transcript expression from dysplasia to early HCC. The lncRNA AK021443 was also up-regulated in advanced HCC samples when compared with early HCC. Moreover, expression of LINC01419 and AK021443 was up-regulated in HCC tissues when compared with non-tumor liver tissue. AF070632 expression was down-regulated in HCC and was decreased in advanced HCC when compared with early HCC. These results suggest that LINC01419 may be related to the initiation of HCC, whereas AK021443 and AF070632 may be associated with the progression of HCC. | 26540467 | Lnc2Cancer | ||