| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0680 | Name | LINC01018 | Aliases | SRHC | |
| Species | Homo sapiens | Chromosome | 5 | Start site | 6582136 | |
| End site | 6588499 | Chain | plus | Exon NO. | 5 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_024423, NR_024424 | |
| Ensembl | ENSG00000250056 | Sequence | ||||
| Disease | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
| hepatocelluar carcinoma | qPCR etc. | HCC tissue, cell lines (BEL-7402, SK-Hep1, Huh7, MHCC-97H) | down-regulated | mutation | We found that a lower SRHC expression level was significantly more frequent in tissues with a high serum a-fetoprotein level and a low degree of differentiated tumors. Furthermore, we found that the promoter region of SRHC contains a CpG-rich island and that SRHC is down-regulated in tumors by DNA methylation. | 25512078 | Lnc2Cancer | ||