LncRNA Information | ||||||
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ID | EL0666 | Name | LINC00668 | Aliases | Long Intergenic Non-Protein Coding RNA 668 | |
Species | Homo sapiens | Chromosome | 18 | Start site | 6919496 | |
End site | 6929966 | Chain | minus | Exon NO. | 7 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_034100 | |
Ensembl | ENSG00000265933 | Sequence |
Disease | |||||||||
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Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
gastric cancer | knockdown | n vitro and in vivo | up-regulated | N/A | LINC00668 knockdown significantly repressed proliferation, both in vitro and in vivo | 27036039 | |||
Interaction | |||||||||
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Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
E2F1 | RNA-TF | regulation | LINC00668 was a direct transcriptional target of E2F transcription factor 1 (E2F1). | 27036039 | |||||
PRC2 | RNA-Protein | regulation | LINC00668 was associated with PRC2 and that this association was required for epigenetic repression of cyclin-dependent protein kinase inhibitors (CKIs), including p15, p16, p21, p27 and p57, thus contributing to the regulation of the gastric cancer cell cycle. | 27036039 | |||||