| Disease |
| Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
| nasopharyngeal carcinoma |
microarray, ISH etc. |
NPC, TMA tissue |
down-regulated |
expression |
Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma. |
23529758 |
LncRNADisease Lnc2Cancer
|
| non-small cell lung cancer |
microarray, qPCR etc. |
NSCLC tissue |
down-regulated |
expression |
The expression level of ADAMTS9-AS2, C1401f132 and LINC00312 in NSCLC tumors were indeed significantly down-regulated when compared with those in normal lung tissues, while LINC00673 was significantly up-regulated in NSCLC tumors compared with normal lung tissues.These lncRNAs could be further exploited for the development of useful biomarkers in diagnosis, prognosis and treatment of NSCLC. |
25590602 |
Lnc2Cancer
|
| nasopharyngeal carcinoma |
N/A |
N/A |
N/A |
expression |
NAG-7 is a novel gene downregulated in human nasopharyngeal carcinoma. |
11780420 |
LncRNADisease
|
| nasopharyngeal carcinoma |
Northern blot, Western blot etc. |
HNE1 cell line |
down-regulated |
expression |
NAG7 (LINC00312) gene re-expression could inhibit overproliferation of NPC cell by delaying the progression of G1 into S in cell cycle and inducing cell apoptosis. |
12452030 |
LncRNADisease Lnc2Cancer
|
| nasopharyngeal carcinoma |
qPCR, Western blot, Luciferase reporter assay, ISH etc. |
cell line (HNE1) |
up-regulated |
Interaction |
NAG7 (LINC00312) promotes human nasopharyngeal carcinoma invasion through inhibition of estrogen receptor alpha and up-regulation of JNK2/AP-1/MMP1 pathways. |
19591174 |
LncRNADisease Lnc2Cancer
|
| |