LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0647 | Name | LINC00160 | Aliases | C21orf52; NCRNA00160 | |
Species | Homo sapiens | Chromosome | 21 | Start site | 34723807 | |
End site | 34737181 | Chain | minus | Exon NO. | 6 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_024351 | |
Ensembl | ENSG00000230978 | Sequence |
Disease | |||||||||
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Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
breast cancer | Single-molecule sequencing, chromatin immunoprecipitation and quantitative real-time PCR | luminal A-type human breast cancer cell lines MCF7 and T47D | up-regulated | interaction | Silencing of LINC00160 results in reduced proliferation, demonstrating that lncRNA expression have functional consequences. | 26423156 | |||
Interaction | |||||||||
---|---|---|---|---|---|---|---|---|---|
Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
ERα | DNA-Protein | regulation | LINC01016 and LINC00160 are direct transcriptional targets of ERα, correlate with Erα expression in clinical samples, and show prognostic significance in relation to breast cancer survival. | 26423156 | |||||