Disease |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
Prader-Willi syndrome |
N/A |
N/A |
N/A |
mutation |
Genetic variation in lncRNA genes causes disease and influences susceptibility |
23791884 |
LncRNADisease
|
Prader-Willi syndrome |
N/A |
N/A |
N/A |
expression |
Subsequently, we determined that IPW, along?noncoding?RNA?in the critical region of the PWS locus, is a regulator of the DLK1-DIO3 region, as its overexpression in PWS and parthenogenetic iPSCs resulted in downregulation of MEGs in this locus.? |
24816254 |
LncRNADisease
|
Prader-Willi syndrome |
N/A |
N/A |
N/A |
locus |
IPW (Imprinted gene in the Prader-Willi syndrome region) was isolated using the direct selection method and yeast artificial chromosomes localized to the deletion region. the mRNA product of IPW may play a role in the imprinting process. |
7849716 |
LncRNADisease
|
Prader-Willi syndrome |
N/A |
N/A |
N/A |
expression |
The Prader-Willi syndrome (PWS) is caused by genomic alterations that inactivate imprinted, paternally expressed genes in human chromosome region 15q11-q13. IPW, a paternally expressed gene cloned from this region, is not expressed in individuals with PWS. |
9063754 |
LncRNADisease
|
|