| Disease |
| Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
| hepatocelluar carcinoma |
microarray, qPCR, RIP, RNA pulldown assay etc. |
HCC tissue, cell lines (Huh7, HepG2) |
up-regulated |
N/A |
The transcript levels of lncRNA-HEIH were higher in HCC tissues (p=0.010) when compared with the corresponding non-tumor liver tissues from the same donor. And we found that patients with high lncRNA-HEIH expression in HCC had significantly worse prognosis than those with low lncRNA-HEIH expression. |
21769904 |
Lnc2Cancer
|
| hepatocelluar carcinoma |
N/A |
N/A |
N/A |
expression |
Dr. Yang and his colleagues found that one lncRNA, named lncRNA-HEIH, was overexpressed in HCC tissue compared with normal liver tissues using microarray. |
24757675 |
LncRNADisease
|
| hepatocelluar carcinoma |
qPCR, Western blot, knockdown etc. |
cell lines (MHCC97L, HepG2, cHL-7702) |
up-regulated |
expression |
The expression of HEIH and HULC in hepatocellular carcinoma cell line was significantly increased compared with human normal hepatocyte line (P<0.05). The expression of HULC in HepG2 was higher than that in MHCC97L. The over-expression of HULC could enhance proliferation of MHCC97L and HepG2, however, the over-expression of HEIH could not. The over-expression of HULC and HEIH could promote invasion of MHCC97L and HepG2. Invasion of MHCC97L and HepG2 did not have significant change after down-regulating of HEIH and HULC by siRNA. Over-expression of HULC up-regulated the expression of Snail in HepG2. |
26550214 |
Lnc2Cancer
|
| |