| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0541 | Name | Gm30731 | Aliases | Pnky; lnc-pou3f2 | |
| Species | Mus musculus | Chromosome | 4 | Start site | 22490548 | |
| End site | 22493126 | Chain | plus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_131335 | |
| Ensembl | ENSMUSG00000107859 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| knockdown | neural stem cell (NSC) in the embryonic and postnatal brain | N/A | Interaction | In NSCs, Pnky and PTBP1 regulate the expression and alternative splicing of a core set of transcripts that relates to the cellular phenotype. These data thus unveil Pnky as a conserved lncRNA that interacts with a key RNA processing factor and regulates neurogenesis from embryonic and postnatal NSC populations. | 25800779 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| PTBP1 | RNA-Protein | binding | Pnky interacts with the splicing regulator PTBP1, and PTBP1 knockdown also enhances neurogenesis. | 25800779 | |||||