LncRNA Information
ID	EL0363	Name	EFNA3	Aliases	EFL2; EPLG3; Ehk1-L; LERK3
Species	Homo sapiens	Chromosome	1	Start site	155078872
End site	155087538	Chain	plus	Exon NO.	5
Assembly	Ensembl Release 89	Class	processed transcript	NCBI accession	N/A
Ensembl	ENSG00000143590	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
breast cancer	qPCR, RIP etc.	breast cancer tissue	up-regulated	N/A	We demonstrate that sustained expression of both Ephrin-A3 and novel EFNA3 lncRNAs increased the metastatic potential of human breast cancer cells, possibly by increasing the ability of tumor cells to extravasate from the blood vessels into surrounding tissue. In agreement, we found a strong correlation between high EFNA3 expression and shorter metastasis-free survival in breast cancer patients. hypoxia could contribute to metastatic spread of breast cancer via HIF-mediated induction ofEFNA3lncRNAs and subsequent Ephrin-A3 protein accumulation.	25023702	Lnc2Cancer