LncRNA Information
ID EL0271 Name CASC15 Aliases LINC00340
Species Homo sapiens Chromosome 6 Start site 21664772
End site 22368328 Chain plus Exon NO. 12
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_015410
Ensembl ENSG00000272168 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
neuroblastoma RNA-seq, qPCR, knockdown, Luciferase reporter assay, RNA-FISH etc. Neuroblastoma cell lines down-regulated mutation Here we report that the most highly significant single-nucleotide polymorphism (SNP) associations reside within CASC15, a long noncoding RNA that we define as a tumor suppressor at 6p22. Low-level expression of a short CASC15 isoform (CASC15-S) associated highly with advanced neuroblastoma and poor patient survival. 26100672 Lnc2Cancer