LncRNA Information
ID EL0985 Name NORAD Aliases LINC00657
Species Homo sapiens Chromosome 20 Start site 36045622
End site 36050960 Chain minus Exon NO. 1
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_027451
Ensembl ENSG00000260032 Sequence

Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
N/A previously karyotypically stable cell lines N/A interaction Inactivation of NORAD triggers dramatic aneuploidy in previously karyotypically stable cell lines. 26724866

Interaction target Level of interaction Type of interaction Description PMID Source
PUMILIO RNA-Protein regulation NORAD maintains genomic stability by sequestering PUMILIO proteins, which repress the stability and translation of mRNAs to which they bind. In the absence of NORAD, PUMILIO proteins drive chromosomal instability by hyperactively repressing mitotic, DNA repair, and DNA replication factors. 26724866