| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0095 | Name | AT102202 | Aliases | N/A | |
| Species | Homo sapiens | Chromosome | N/A | Start site | N/A | |
| End site | N/A | Chain | N/A | Exon NO. | N/A | |
| Assembly | N/A | Class | N/A | NCBI accession | N/A | |
| Ensembl | N/A | Sequence | N/A | |||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| Microarrays, RT-PCR | cultured human liver (HepG2) hepatocytes treated with epigallocatechin-3-gallate( EGCG) | up-regulated | expression | Using a real-time polymerase chain reaction technique, we confirmed that EGCG down-regulated mRNA expression level of the HMGCR and up-regulated expression of AT102202. After AT102202 knockdown in HepG2, weobserved that the level of HMGCR expression was significantly increased relative to the scrambled small interfering RNA control (P < 0.05). | 25563320 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| mRNA-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) | RNA-Protein | regulation | In particular, the lncRNA AT102202 and its potential targets mRNA-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) were identified. | 25563320 | |||||