LncRNA Information
ID EL0933 Name MR1 Aliases HLALS
Species Homo sapiens Chromosome 1 Start site 181033425
End site 181061938 Chain plus Exon NO. 8
Assembly Ensembl Release 89 Class retained intron NCBI accession N/A
Ensembl ENSG00000153029 Sequence N/A

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
Loeys-Dietz syndrome (LDS) RT-PCR aortic aneurysm patients differential expression interaction LncRNA AK056155 was differentially expressed in peripheral blood circulating endothelial cells between normal patients and LDS patients by bioinformatics. AK056155 was also overexpressed in aortic aneurysm patients by RT-PCR. 26617788

Interaction target Level of interaction Type of interaction Description PMID Source
TGF-β1; PI3K inhibitor (LY294002); AKT inhibitor (GDC-0068) DNA-Protein regulation the expression of AK056155 can be enhanced by TGF-β1 in a concentration or time depended manner in HUVECs by RT-PCR. Furthermore, the expression of AK056155 was reduced with treatment of PI3K inhibitor (LY294002) or AKT inhibitor (GDC-0068) in combination with TGF-β1. 26617788