LncRNA Information
ID EL0932 Name MNX1-AS1 Aliases CCAT5
Species Homo sapiens Chromosome 7 Start site 157010805
End site 157016426 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_038835
Ensembl ENSG00000243479 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
ovarian cancer microarray, qPCR etc. ovarian cancer tissue, cell lines (SKOV3, SKOV3.ip1 etc.) down-regulated N/A The qPCR results of seven lncRNAs (MALAT1, H19, UCA1, CCAT1, LOC645249, LOC100128881, and LOC100292680) were consistent with the deregulation found by microarray analysis, reflecting the reliability of the microarray data to some extent. 24379988 Lnc2Cancer
colorectal cancer microarray, qPCR, Luciferase reporter assay etc. CRC tissue, cell lines (HCT116, RKO, HT29, SW620 etc.) up-regulated expression Of the seletced lncRNAs, four lncRNAs named CCAT3, CCAT4, CCAT5, and CCAT6 (also named MYCLo-2) are upregulated in CRC cell lines, and two lncRNAs named CCAT7 and CCAT8 are downregulated in CRC cell lines. MYC-regulated lncRNAs, named MYCLos. The MYC-regulated MYCLos may function in cell proliferation and cell cycle by regulating MYC target genes such as CDKN1A (p21) and CDKN2B (p15), suggesting new regulatory mechanisms of MYC-repressed target genes through lncRNAs. 25663692 Lnc2Cancer