LncRNA Information
ID EL0881 Name MIR4435-2HG Aliases AGD2; AK001796; LINC00978; MIR4435-1HG
Species Homo sapiens Chromosome 2 Start site 111196350
End site 111495100 Chain minus Exon NO. 10
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_136164, NR_136163, NR_136162, NR_136165, NR_136161, NR_136166, NR_015395, NR_024373
Ensembl ENSG00000172965 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
lung cancer microarray, qRT-PCR lung cancer tissues and A549 cell lines up-regulated expression We observed a significant reduction in cell viability in lung cancer cells and a slow growth in the tumorigenesis following AK001796 knockdown. We also found that AK001796 knockdown caused a cell-cycle arrest, with significant increases in the percentage of cells in G0/G1 in lung cancer cells. Reduced lncRNA AK001796 level potentially impaired the inhibitory effect of resveratrol on cell proliferation. 25888808