| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0865 | Name | MHM | Aliases | N/A | |
| Species | Gallus gallus | Chromosome | N/A | Start site | N/A | |
| End site | N/A | Chain | N/A | Exon NO. | N/A | |
| Assembly | N/A | Class | N/A | NCBI accession | N/A | |
| Ensembl | N/A | Sequence | N/A | |||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| expression analysis and retroviral-mediated mis-expression,Northern blot,Whole mount in situ hybridization | chicken embryo | N/A | N/A | MHM has a role in chicken normal embryonic development, including gonadal sex differentiation. | 22546690 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| DMRT1 | RNA-DNA | regulation | Mis-expression of MHM sense and antisense sequences results in overgrowth of tissues in which transcripts are predominantly expressed. This includes altered asymmetric ovarian development in females. In males, MHM mis-expression impairs gonadal expression of the testis gene, DMRT1. Both MHM sense and antisense mis-expression cause brain abnormalities, while MHM sense causes an increase in male-biased embryo mortality. | 22546690 | |||||