LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0082 | Name | APTR | Aliases | RSBN1L-AS1 | |
Species | Homo sapiens | Chromosome | 7 | Start site | 77657660 | |
End site | 77696265 | Chain | minus | Exon NO. | 5 | |
Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_134251, NR_134254, NR_134253, NR_038361 | |
Ensembl | ENSG00000214293 | Sequence |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
glioblastoma | qPCR, Northern blot, Luciferase reporter assays, knockdown etc. | primary glioblastoma tissue, cell lines (A172, HCT116) | up-regulated | N/A | We identified a novel lncRNA, APTR, that acts in trans to repress the CDKN1A/p21 promoter independent of p53 to promote cell proliferation. | 24748121 | Lnc2Cancer | ||