LncRNA Information
ID EL0810 Name lnc-ZNF180-2 Aliases lnc-ZNF180-2
Species Homo sapiens Chromosome 19 Start site 44474428
End site 44500524 Chain minus Exon NO. N/A
Assembly Ensembl Release 89 Class N/A NCBI accession N/A
Ensembl ENSG00000167384 Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
clear cell renal cell carcinoma microarray, qPCR etc. ccRCC tissue down-regulated expression lnc-ZNF180-2 levels were similar in localized ccRCC and normal renal tissue, but we observed a significant increase of lnc-ZNF180-2 expression in advanced ccRCC tissue. Furthermore, lnc-ZNF180-2 expression levels were an independent predictor of progression-free survival, cancer-specific survival and overall survival in ccRCC patients. We also observed that lnc-CYP4A22-2/3 expression levels allowed discrimination of ccRCC and normal renal tissue. In conclusion, lncRNAs are involved in renal carcinogenesis, and quantification of lnc-ZNF180-2 may be useful for the prediction of ccRCC patients outcome following nephrectomy. 26609485 Lnc2Cancer