LncRNA Information
ID EL0080 Name APOA1-AS Aliases N/A
Species Homo sapiens Chromosome 11 Start site 116836117
End site 116855729 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_126362
Ensembl ENSG00000235910 Sequence


Function (not disease relevant)
Methods Sample/condition Expression pattern Dysfunction type Description PMID Source
Chromatin immunoprecipitation (ChIP) analyses, Targeting APOA1-AS with short antisense oligonucleotides human and monkey liver cells down-regulated N/A acts as a negative transcriptional regulator of APOA1 both in vitro and in vivo. Inhibition of APOA1-AS in cultured cells resulted in the increased expression of APOA1 and two neighboring genes in the APO cluster. 24388749
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
APOA1 RNA-Protein regulation APOA1-AS can modulate distinct histone methylation patterns that mark active and/or inactive gene expression through the recruitment of histone-modifying enzymes. 24388749