clear cell renal cell carcinoma |
microarray, qPCR etc. |
ccRCC tissue |
down-regulated |
expression |
Among these, aberrant expression was validated using PCR: lnc-BMP2-2, lnc-CPN2-1, lnc-FZD1-2, lnc-ITPR2-3, lnc-SLC30A4-1, and lnc-SPAM1-6 were highly overexpressed in ccRCC, whereas lnc-ACACA-1, lnc-FOXG1-2, lnc-LCP2-2, lnc-RP3-368B9, and lnc-TTC34-3 were downregulated. Computational analyses revealed that these lncRNAs are involved in RNA-protein networks related to splicing, binding, transport, localization, and processing of RNA. |
25685243 |
Lnc2Cancer
|