Disease |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
tongue cancer |
RNA-seq, qPCR etc. |
cell lines (UMSCC-10B, HN-12) |
down-regulated |
N/A |
We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. |
25904139 |
LncRNADisease Lnc2Cancer
|
pharyngeal cancer |
RNA-seq, qPCR etc. |
cell lines (HN-1, HN-30) |
down-regulated |
N/A |
We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. |
25904139 |
LncRNADisease Lnc2Cancer
|
laryngeal cancer |
RNA-seq, qPCR etc. |
cell lines (UMSCC-22B) |
down-regulated |
N/A |
We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. |
25904139 |
LncRNADisease Lnc2Cancer
|
|