LncRNA Information
ID	EL0768	Name	lnc-DILC	Aliases	N/A
Species	Homo sapiens	Chromosome	N/A	Start site	N/A
End site	N/A	Chain	N/A	Exon NO.	N/A
Assembly	N/A	Class	N/A	NCBI accession	N/A
Ensembl	N/A	Sequence	N/A

Disease
Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
liver cancer	real-time PCR; pull down assay and oligoribonucleotides or oligodeoxynucleotides treatment	N/A	down-regulated	interaction	Depletion of lnc-DILC markedly enhanced LCSC expansion and facilitated HCC initiation and progression, whereas ectopic expression of lnc-DILC dramatically inhibited LCSC expansion. Mechanistically, lnc-DILC inhibited the autocrine IL-6/STAT3 signaling.	26812074

Interaction
Interaction target	Level of interaction	Type of interaction	Description	PMID	Source
interleukin-6 (IL-6) promoter	RNA-Protein	regulation	lnc-DILC mediates the crosstalk between TNF-α/NF-κB signaling and autocrine IL-6/STAT3 cascade and connects hepatic inflammation with LCSC expansion	26812074
TNF-α/NF-κB	RNA-Protein	regulation	lnc-DILC mediates the crosstalk between TNF-α/NF-κB signaling and autocrine IL-6/STAT3 cascade and connects hepatic inflammation with LCSC expansion	26812074
STAT3	RNA-Protein	regulation	STAT3 activation and LCSC expansion triggered by lnc-DILC depletion and lnc-DILC overexpression.	26812074