LncRNA Information
ID EL0745 Name lincRNA-TSPAN8 Aliases N/A
Species Homo sapiens Chromosome N/A Start site N/A
End site N/A Chain N/A Exon NO. N/A
Assembly N/A Class N/A NCBI accession N/A
Ensembl N/A Sequence N/A


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
hepatocelluar carcinoma microarray, qPCR etc. cell lines (Hep3B, HepG2, SMMC-7721, MHCC-97L, MHCC-97H, HCCLM3 etc.) down-regulated expression The most upregulated lncRNAs in H2 were RP11-672F9.1, RP5-1014O16.1, and RP11-501G6.1, while the most downregulated ones were lincRNA-TSPAN8, lincRNA-CALCA, C14orf132, NCRNA00173, and CR613944. Among them, lincRNA-TSPAN8 and TSPAN8 were found highly expressed in high lung metastatic potential HCC cells, while lowly expressed in no or low lung metastatic potential HCC cells. We demonstrated that a large number of lncRNAs may play important roles in driving HCC cells to metastasize to different sites; these lncRNAs may provide novel molecular biomarkers and offer a new basis for combating metastasis in HCC cases. 25556502 Lnc2Cancer