LncRNA Information
ID EL0677 Name LINC00982 Aliases LINC00982; FLJ42875
Species Homo sapiens Chromosome 1 Start site 3059615
End site 3068437 Chain minus Exon NO. 6
Assembly Ensembl Release 89 Class antisense NCBI accession NR_015440, NR_024371
Ensembl ENSG00000177133 Sequence


Disease
Disease Method Sample Expression pattern Dysfunction type Description PMID Source
gastric cancer qPCR, Western blot, Luciferase reporter assay, knockdown, RIP etc. gastric cancer tissue, cell lines (SGC7901, BGC823, MGC803, AGS, MKN45) down-regulated interaction In this study, we identified a novel lncRNA LINC00982, whose expression was downregulated in tumor tissues in 106 patients with gastric cancer (GC) compared with those in the adjacent normal tissues (P < 0.001). Furthermore, knockdown of LINC00982 expression by small interfering RNA (siRNA) could promote cell proliferation and cell cycle progression, while ectopic expression of LINC00982 inhibited cell proliferation and rendered cell cycle arrest in GC cells partly via regulating P15 and P16 protein expressions. 26334618 Lnc2Cancer
 


Interaction
Interaction target Level of interaction Type of interaction Description PMID Source
P15 and P16 protein RNA-Protein regulation Ectopic expression of LINC00982 inhibited cell proliferation and rendered cell cycle arrest in GC cells partly via regulating P15 and P16 protein expressions. 26334618