LncRNA Information
ID EL0670 Name LINC00901 Aliases LSAMP-AS4; TCONS_00005428
Species Homo sapiens Chromosome 3 Start site 116921431
End site 116932238 Chain plus Exon NO. 2
Assembly Ensembl Release 89 Class antisense NCBI accession NR_121607
Ensembl ENSG00000242385 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
osteosarcoma microarray, qPCR, FISH etc. osteosarcoma tissue, cell lines (U2OS, SAOS-2, HOS etc.) down-regulated mutation These CNAs (copy number alterations) in osteosarcoma often involve the noncoding RNAs LOC285194 and BC040587. 20048075 LncRNADisease Lnc2Cancer
gastric cancer microarray, qPCR, knockdown etc. gastric cancer tissue down-regulated N/A LncRNA M59227 and 3 mRNAs, PLK1, PTTG1 and VCAN, were overexpressed in GC. In contrast, the expression of 4 lncRNAs, LOC150622, AKR7 L, DQ192290 and BC040587, and 2 mRNAs, DRD5 and GDF5, were downregulated in GC.The results indicated that TUSC7 is a p53-regulated tumour suppressor that acts in part by repressing miR-23b and that TUSC7 may be a key regulatory hub in GC. 25765901 LncRNADisease Lnc2Cancer
breast cancer qPCR etc. breast cancer tissue, cell lines (ZR-75-30, MCF-7, SKBR-3, T47D cells) down-regulated expression It showed that BC040587 expression was down regulated both in BC samples and in BC cell lines compared with corresponding normal control. BC040587 expression was correlated with menopausal status and tumor differentiation. Furthermore, expression of BC040587 was significantly associated with worse prognosis and was shown to be an independent prognostic marker breast cancer. 25435812 Lnc2Cancer