LncRNA Information
ID EL0666 Name LINC00668 Aliases Long Intergenic Non-Protein Coding RNA 668
Species Homo sapiens Chromosome 18 Start site 6919496
End site 6929966 Chain minus Exon NO. 7
Assembly Ensembl Release 89 Class lincRNA NCBI accession NR_034100
Ensembl ENSG00000265933 Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
gastric cancer knockdown n vitro and in vivo up-regulated N/A LINC00668 knockdown significantly repressed proliferation, both in vitro and in vivo 27036039

Interaction target Level of interaction Type of interaction Description PMID Source
E2F1 RNA-TF regulation LINC00668 was a direct transcriptional target of E2F transcription factor 1 (E2F1). 27036039
PRC2 RNA-Protein regulation LINC00668 was associated with PRC2 and that this association was required for epigenetic repression of cyclin-dependent protein kinase inhibitors (CKIs), including p15, p16, p21, p27 and p57, thus contributing to the regulation of the gastric cancer cell cycle. 27036039