LncRNA Information
ID EL0654 Name LINC00312 Aliases ERR-10; ERR10; LMCD1DN; LOH3CR2A; NAG-7; NAG7; NCRNA00312
Species Homo sapiens Chromosome 3 Start site 8571782
End site 8574668 Chain plus Exon NO. 1
Assembly GRCh38.p7 Class N/A NCBI accession NR_024065
Ensembl N/A Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
nasopharyngeal carcinoma microarray, ISH etc. NPC, TMA tissue down-regulated expression Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma. 23529758 LncRNADisease Lnc2Cancer
non-small cell lung cancer microarray, qPCR etc. NSCLC tissue down-regulated expression The expression level of ADAMTS9-AS2, C1401f132 and LINC00312 in NSCLC tumors were indeed significantly down-regulated when compared with those in normal lung tissues, while LINC00673 was significantly up-regulated in NSCLC tumors compared with normal lung tissues.These lncRNAs could be further exploited for the development of useful biomarkers in diagnosis, prognosis and treatment of NSCLC. 25590602 Lnc2Cancer
nasopharyngeal carcinoma N/A N/A N/A expression NAG-7 is a novel gene downregulated in human nasopharyngeal carcinoma. 11780420 LncRNADisease
nasopharyngeal carcinoma Northern blot, Western blot etc. HNE1 cell line down-regulated expression NAG7 (LINC00312) gene re-expression could inhibit overproliferation of NPC cell by delaying the progression of G1 into S in cell cycle and inducing cell apoptosis. 12452030 LncRNADisease Lnc2Cancer
nasopharyngeal carcinoma qPCR, Western blot, Luciferase reporter assay, ISH etc. cell line (HNE1) up-regulated Interaction NAG7 (LINC00312) promotes human nasopharyngeal carcinoma invasion through inhibition of estrogen receptor alpha and up-regulation of JNK2/AP-1/MMP1 pathways. 19591174 LncRNADisease Lnc2Cancer

Interaction target Level of interaction Type of interaction Description PMID Source
ERA RNA-DNA regulation ERR-10 (LINC00312): a new repressor in transcriptional signaling activation of estrogen receptor-alpha. 15474036 LncRNADisease