LncRNA Information
ID EL0640 Name LCAL1 Aliases onco-lncRNA-27
Species Homo sapiens Chromosome 6 Start site 79307669
End site 79313384 Chain minus Exon NO. 3
Assembly GRCh38.p7 Class N/A NCBI accession NR_130915
Ensembl N/A Sequence

Disease Method Sample Expression pattern Dysfunction type Description PMID Source
lung cancer RNA-Seq, qPCR, knockdown etc. lung cancer tissue up-regulated expression Stable overexpression of LCAL1, using two different clones, in the control cell line BEAS-2B showed a significant increase in cellular proliferation starting on day 2 and continuing until the end of the experiment at day 6 with a 38% and 43% growth increase, respetcively. Overexpression of LCAL1 in normal BEAS-2B cells is proof of principle that this lncRNA is sufficient to affetc cellular growth independently of other common cancer mutations, thus highlighting the importance of LCAL1 in lung cancer biology. 25116943 Lnc2Cancer