LncRNA Information | ||||||
---|---|---|---|---|---|---|
ID | EL0006 | Name | 51A | Aliases | antisense to intron 1 of the SORL1 gene | |
Species | Homo sapiens | Chromosome | 19 | Start site | 58770915 | |
End site | 58770934 | Chain | minus | Exon NO. | N/A | |
Assembly | N/A | Class | N/A | NCBI accession | N/A | |
Ensembl | N/A | Sequence | N/A |
Disease | |||||||||
---|---|---|---|---|---|---|---|---|---|
Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source | ||
Alzheimer's disease | N/A | N/A | N/A | regulation | 51A expression drives a splicing shift of SORL1 from the synthesis of the canonical long protein variant 1 to an alternatively spliced protein form. This process, resulting in a decreased synthesis of SORL1 variant 1, is associated with an impaired processing of APP, leading to increase of A formation. | 22996644 | LncRNADisease | ||