| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0594 | Name | HSUR1 | Aliases | Herpesvirus saimiri U RNAs | |
| Species | Herpesvirus saimiri | Chromosome | N/A | Start site | N/A | |
| End site | N/A | Chain | N/A | Exon NO. | N/A | |
| Assembly | N/A | Class | N/A | NCBI accession | N/A | |
| Ensembl | N/A | Sequence | N/A | |||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| Microarray and Northern analyses | N/A | N/A | interaction | An unexpected role for the hsurs in regulating a remarkably defined and physiologically relevant set of host targets involved in the activation of virally transformed t cells during latency. | 15916956 | ||||
| N/A | T cells | N/A | Interaction | HSURs 1 and 2 interact with the predicted miRNAs in virally transformed T cells. | 20558719 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| host mRNAs | RNA-RNA | regulation | Hsur 1 and 2 expression correlates with significant increases in a small number of host mrnas, including the t cell-receptor beta and gamma chains, the t cell and natural killer (nk) cell-surface receptors cd52 and dap10, and intracellular proteins--skap55, granulysin, and nkg7--linked to t cell and nk cell activation. | 15916956 | |||||
| miR-27 | RNA-RNA | binding | Transient knockdown and ectopic expression of HSUR 1 demonstrate that it directs degradation of mature miR-27 in a sequence-specific and binding-dependent manner. | 20558719 | |||||