| LncRNA Information | ||||||
|---|---|---|---|---|---|---|
| ID | EL0560 | Name | Halr1 | Aliases | Gm15055; Haunt; Linchoxa1; OTTMUSG00000018881; linc-Evx1; linc-Hoxa1; linc1547 | |
| Species | Mus musculus | Chromosome | 6 | Start site | 52102949 | |
| End site | 52113684 | Chain | plus | Exon NO. | 3 | |
| Assembly | Ensembl Release 89 | Class | lincRNA | NCBI accession | NR_110440 | |
| Ensembl | ENSMUSG00000085412 | Sequence | ||||
| Function (not disease relevant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | Sample/condition | Expression pattern | Dysfunction type | Description | PMID | Source | |||
| knockdown | mouse embryonic stem cells | N/A | interaction | Depletion of linc-HOXA1 RNA at its site of transcription increased transcription of the Hoxa1 gene cis to the chromosome and that exposure of cells to retinoic acid can disrupt this interaction. | 23723417 | ||||
| knockdown, Screening for pluripotency affects, Lineage expression affects, TF binding and regulation, Chromatin binding and overlap in expression | mouse embryonic stem (ES) cells | N/A | interaction | Involved in maintaining pluripotency in ESCs. | 21874018 | ||||
| Interaction | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interaction target | Level of interaction | Type of interaction | Description | PMID | Source | ||||
| Hoxa1 | RNA-DNA | regulation | linc-HOXA1 RNA represses Hoxa1 by recruiting the protein PURB as a transcriptional cofactor. | 23723417 | |||||
| PURB | RNA-Protein | regulation | linc-HOXA1 RNA represses Hoxa1 by recruiting the protein PURB as a transcriptional cofactor. | 23723417 | |||||